BDBM50307443 3-{2-({[1-(3,5-Dimethylphenyl)-3-methylbutyl]amino}-carbonyl)-4-[(3-methoxyphenoxy)methyl]phenyl}propanoic acid::CHEMBL599405

SMILES: COc1cccc(OCc2ccc(CCC(O)=O)c(c2)C(=O)NC(CC(C)C)c2cc(C)cc(C)c2)c1

InChI Key: InChIKey=KEVNXEQSUVGTNP-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307443   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid EP3 Receptor (Mus musculus (Mouse))	BDBM50307443 (3-{2-({[1-(3,5-Dimethylphenyl)-3-methylbutyl]amino...) Show SMILES COc1cccc(OCc2ccc(CCC(O)=O)c(c2)C(=O)NC(CC(C)C)c2cc(C)cc(C)c2)c1 Show InChI InChI=1S/C31H37NO5/c1-20(2)13-29(25-15-21(3)14-22(4)16-25)32-31(35)28-17-23(9-10-24(28)11-12-30(33)34)19-37-27-8-6-7-26(18-27)36-5/h6-10,14-18,20,29H,11-13,19H2,1-5H3,(H,32,35)(H,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membrane				Bioorg Med Chem 18: 1641-58 (2010) Article DOI: 10.1016/j.bmc.2009.12.068 BindingDB Entry DOI: 10.7270/Q29023W2
					More data for this Ligand-Target Pair
Prostanoid EP3 Receptor (Mus musculus (Mouse))	BDBM50307443 (3-{2-({[1-(3,5-Dimethylphenyl)-3-methylbutyl]amino...) Show SMILES COc1cccc(OCc2ccc(CCC(O)=O)c(c2)C(=O)NC(CC(C)C)c2cc(C)cc(C)c2)c1 Show InChI InChI=1S/C31H37NO5/c1-20(2)13-29(25-15-21(3)14-22(4)16-25)32-31(35)28-17-23(9-10-24(28)11-12-30(33)34)19-37-27-8-6-7-26(18-27)36-5/h6-10,14-18,20,29H,11-13,19H2,1-5H3,(H,32,35)(H,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Antagonist activity at mouse EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase intracellular calcium level in prese...				Bioorg Med Chem 18: 1641-58 (2010) Article DOI: 10.1016/j.bmc.2009.12.068 BindingDB Entry DOI: 10.7270/Q29023W2
					More data for this Ligand-Target Pair