BindingDB logo
myBDB logout

null

SMILES: CN(CCNS(=O)(=O)c1cccc2c(cccc12)N(C)C)CCN=NNc1ccc2ncnc(Nc3cccc(Cl)c3)c2c1

InChI Key: InChIKey=KYVRWAGUEBMRLC-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307929   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50307929
PNG
(CHEMBL591897 | N-(2-((2-(3-(4-(3-chlorophenylamino...)
Show SMILES CN(CCNS(=O)(=O)c1cccc2c(cccc12)N(C)C)CCN=NNc1ccc2ncnc(Nc3cccc(Cl)c3)c2c1 |w:23.24|
Show InChI InChI=1S/C31H34ClN9O2S/c1-40(2)29-11-5-10-26-25(29)9-6-12-30(26)44(42,43)36-16-18-41(3)17-15-35-39-38-24-13-14-28-27(20-24)31(34-21-33-28)37-23-8-4-7-22(32)19-23/h4-14,19-21,36H,15-18H2,1-3H3,(H,35,38)(H,33,34,37)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 600n/an/an/an/an/an/a



McGill University Health Center/Royal Victoria Hospital

Curated by ChEMBL


Assay Description
Inhibition of EGFR

J Med Chem 53: 2104-13 (2010)


Article DOI: 10.1021/jm9016043
BindingDB Entry DOI: 10.7270/Q2BV7GQ6
More data for this
Ligand-Target Pair