BindingDB logo
myBDB logout

null

SMILES: NC1(Cc2ccc(Cl)cc2Cl)CCN(CC1)c1ncnc2[nH]c(=O)[nH]c12

InChI Key: InChIKey=UTOUZRCPKJQTHW-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307944   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-beta serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM50307944
PNG
(6-(4-Amino-4-(2,4-dichlorobenzyl)piperidin-1-yl)-7...)
Show SMILES NC1(Cc2ccc(Cl)cc2Cl)CCN(CC1)c1ncnc2[nH]c(=O)[nH]c12
Show InChI InChI=1S/C17H18Cl2N6O/c18-11-2-1-10(12(19)7-11)8-17(20)3-5-25(6-4-17)15-13-14(21-9-22-15)24-16(26)23-13/h1-2,7,9H,3-6,8,20H2,(H2,21,22,23,24,26)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 52n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of PKBbeta by radiometric filter binding assay

J Med Chem 53: 2239-49 (2010)


Article DOI: 10.1021/jm901788j
BindingDB Entry DOI: 10.7270/Q23B608V
More data for this
Ligand-Target Pair