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SMILES: CC(C)(C)c1ccc(CC2(N)CCN(CC2)c2ncnc3[nH]c(=O)[nH]c23)cc1

InChI Key: InChIKey=CENSOIHHGQYIKW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307947   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-beta serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM50307947
PNG
(6-(4-Amino-4-(4-tert-butylbenzyl)piperidin-1-yl)-7...)
Show SMILES CC(C)(C)c1ccc(CC2(N)CCN(CC2)c2ncnc3[nH]c(=O)[nH]c23)cc1
Show InChI InChI=1S/C21H28N6O/c1-20(2,3)15-6-4-14(5-7-15)12-21(22)8-10-27(11-9-21)18-16-17(23-13-24-18)26-19(28)25-16/h4-7,13H,8-12,22H2,1-3H3,(H2,23,24,25,26,28)
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Article
PubMed
n/an/a 70n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of PKBbeta by radiometric filter binding assay

J Med Chem 53: 2239-49 (2010)


Article DOI: 10.1021/jm901788j
BindingDB Entry DOI: 10.7270/Q23B608V
More data for this
Ligand-Target Pair