BDBM50307950 4-Amino-N-(4-tert-butylbenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide::CHEMBL606200

SMILES: CC(C)(C)c1ccc(CNC(=O)C2(N)CCN(CC2)c2ncnc3[nH]ccc23)cc1

InChI Key: InChIKey=DTMJEFNBUJEXCT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307950   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50307950 (4-Amino-N-(4-tert-butylbenzyl)-1-(7H-pyrrolo[2,3-d...) Show SMILES CC(C)(C)c1ccc(CNC(=O)C2(N)CCN(CC2)c2ncnc3[nH]ccc23)cc1 Show InChI InChI=1S/C23H30N6O/c1-22(2,3)17-6-4-16(5-7-17)14-26-21(30)23(24)9-12-29(13-10-23)20-18-8-11-25-19(18)27-15-28-20/h4-8,11,15H,9-10,12-14,24H2,1-3H3,(H,26,30)(H,25,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of PKBbeta by radiometric filter binding assay				J Med Chem 53: 2239-49 (2010) Article DOI: 10.1021/jm901788j BindingDB Entry DOI: 10.7270/Q23B608V
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