BDBM50308484 (2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-heptyl-1,3,4-thiadiazol-2-yl)methyl)phenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol::CHEMBL589324::US8541380, 34
SMILES: CCCCCCCc1nnc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)s1
InChI Key: InChIKey=WRCPYNKCFOFQCH-OSKXVONFSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50308484 ((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-heptyl-1,3,4-th...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 122 | n/a | n/a | n/a | n/a | n/a | n/a |
Green Cross Corporation Curated by ChEMBL | Assay Description Inhibition of human recombinant SGLT2 expressed in CHO cells by liquid scintillation counting | Bioorg Med Chem 18: 2178-94 (2010) Article DOI: 10.1016/j.bmc.2010.01.073 BindingDB Entry DOI: 10.7270/Q2MG7QF6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50308484 ((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-heptyl-1,3,4-th...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 122 | n/a | n/a | n/a | n/a | n/a | n/a |
Green Cross Corporation US Patent | Assay Description Inhibition assay using hSGLT2. | US Patent US8541380 (2013) BindingDB Entry DOI: 10.7270/Q2T43RQ3 | |||||||||||
More data for this Ligand-Target Pair |