BDBM50308500 CHEMBL590301::Ethyl 5-(4-methoxybenzoyl)-4-phenylthiazol-2-ylcarbamate

SMILES: CCOC(=O)Nc1nc(c(s1)C(=O)c1ccc(OC)cc1)-c1ccccc1

InChI Key: InChIKey=JIYLUSOKVKCFJF-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50308500   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50308500 (CHEMBL590301 | Ethyl 5-(4-methoxybenzoyl)-4-phenyl...) Show SMILES CCOC(=O)Nc1nc(c(s1)C(=O)c1ccc(OC)cc1)-c1ccccc1 Show InChI InChI=1S/C20H18N2O4S/c1-3-26-20(24)22-19-21-16(13-7-5-4-6-8-13)18(27-19)17(23)14-9-11-15(25-2)12-10-14/h4-12H,3H2,1-2H3,(H,21,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortex membrane				Bioorg Med Chem 18: 2195-203 (2010) Article DOI: 10.1016/j.bmc.2010.01.072 BindingDB Entry DOI: 10.7270/Q2BZ670J
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50308500 (CHEMBL590301 | Ethyl 5-(4-methoxybenzoyl)-4-phenyl...) Show SMILES CCOC(=O)Nc1nc(c(s1)C(=O)c1ccc(OC)cc1)-c1ccccc1 Show InChI InChI=1S/C20H18N2O4S/c1-3-26-20(24)22-19-21-16(13-7-5-4-6-8-13)18(27-19)17(23)14-9-11-15(25-2)12-10-14/h4-12H,3H2,1-2H3,(H,21,22,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Binding affinity to human adenosine A3 receptor				Bioorg Med Chem 18: 2195-203 (2010) Article DOI: 10.1016/j.bmc.2010.01.072 BindingDB Entry DOI: 10.7270/Q2BZ670J
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50308500 (CHEMBL590301 | Ethyl 5-(4-methoxybenzoyl)-4-phenyl...) Show SMILES CCOC(=O)Nc1nc(c(s1)C(=O)c1ccc(OC)cc1)-c1ccccc1 Show InChI InChI=1S/C20H18N2O4S/c1-3-26-20(24)22-19-21-16(13-7-5-4-6-8-13)18(27-19)17(23)14-9-11-15(25-2)12-10-14/h4-12H,3H2,1-2H3,(H,21,22,24)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Displacement of [3H]PSB-603 from human adenosine A2B receptor expressed in CHO cells				Bioorg Med Chem 18: 2195-203 (2010) Article DOI: 10.1016/j.bmc.2010.01.072 BindingDB Entry DOI: 10.7270/Q2BZ670J
					More data for this Ligand-Target Pair
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM50308500 (CHEMBL590301 | Ethyl 5-(4-methoxybenzoyl)-4-phenyl...) Show SMILES CCOC(=O)Nc1nc(c(s1)C(=O)c1ccc(OC)cc1)-c1ccccc1 Show InChI InChI=1S/C20H18N2O4S/c1-3-26-20(24)22-19-21-16(13-7-5-4-6-8-13)18(27-19)17(23)14-9-11-15(25-2)12-10-14/h4-12H,3H2,1-2H3,(H,21,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.84E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Displacement of [3H]MSX2 from adenosine A2A receptor in rat brain striatum membrane				Bioorg Med Chem 18: 2195-203 (2010) Article DOI: 10.1016/j.bmc.2010.01.072 BindingDB Entry DOI: 10.7270/Q2BZ670J
					More data for this Ligand-Target Pair