BDBM50308751 3-(methyl-N-ethylcarbamate)-6-(N0-ethylphenylamino)indazol-4,7-dione::CHEMBL589095

SMILES: CCN(c1ccccc1)c1cc(O)c2c(CC=NC(=O)OC)n[nH]c2c1O

InChI Key: InChIKey=PYHCSJREOUWUCF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308751   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50308751 (3-(methyl-N-ethylcarbamate)-6-(N0-ethylphenylamino...) Show SMILES CCN(c1ccccc1)c1cc(O)c2c(CC=NC(=O)OC)n[nH]c2c1O |w:16.16| Show InChI InChI=1S/C19H20N4O4/c1-3-23(12-7-5-4-6-8-12)14-11-15(24)16-13(9-10-20-19(26)27-2)21-22-17(16)18(14)25/h4-8,10-11,24-25H,3,9H2,1-2H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Howard University Curated by ChEMBL					Assay Description Displacement of menadione from human recombinant CBR expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem 18: 134-41 (2010) Article DOI: 10.1016/j.bmc.2009.11.011 BindingDB Entry DOI: 10.7270/Q2XG9R7G
					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Homo sapiens (Human))	BDBM50308751 (3-(methyl-N-ethylcarbamate)-6-(N0-ethylphenylamino...) Show SMILES CCN(c1ccccc1)c1cc(O)c2c(CC=NC(=O)OC)n[nH]c2c1O |w:16.16| Show InChI InChI=1S/C19H20N4O4/c1-3-23(12-7-5-4-6-8-12)14-11-15(24)16-13(9-10-20-19(26)27-2)21-22-17(16)18(14)25/h4-8,10-11,24-25H,3,9H2,1-2H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Howard University Curated by ChEMBL					Assay Description Displacement of daunorubicin from human recombinant CBR expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem 18: 134-41 (2010) Article DOI: 10.1016/j.bmc.2009.11.011 BindingDB Entry DOI: 10.7270/Q2XG9R7G
					More data for this Ligand-Target Pair