BDBM50308905 3-[2-({[3-Methyl-1-(1-naphthyl)butyl]amino}carbonyl)-4-(phenoxymethyl)phenyl]propanoic acid::CHEMBL596903
SMILES: CC(C)CC(NC(=O)c1cc(COc2ccccc2)ccc1CCC(O)=O)c1cccc2ccccc12
InChI Key: InChIKey=QIZFGKHZAGUMOI-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostanoid EP3 Receptor (Mus musculus (Mouse)) | BDBM50308905 (3-[2-({[3-Methyl-1-(1-naphthyl)butyl]amino}carbony...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]PGE3alpha from mouse EP3alpha receptor expressed in CHO cells by liquid scintillation counting | Bioorg Med Chem 18: 80-90 (2010) Article DOI: 10.1016/j.bmc.2009.11.023 BindingDB Entry DOI: 10.7270/Q24X57X2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP4 Receptor (Mus musculus (Mouse)) | BDBM50308905 (3-[2-({[3-Methyl-1-(1-naphthyl)butyl]amino}carbony...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]PGE3 from mouse EP4 receptor expressed in CHO cells by liquid scintillation counting | Bioorg Med Chem 18: 80-90 (2010) Article DOI: 10.1016/j.bmc.2009.11.023 BindingDB Entry DOI: 10.7270/Q24X57X2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP2 Receptor (Mus musculus (Mouse)) | BDBM50308905 (3-[2-({[3-Methyl-1-(1-naphthyl)butyl]amino}carbony...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells by liquid scintillation counting | Bioorg Med Chem 18: 80-90 (2010) Article DOI: 10.1016/j.bmc.2009.11.023 BindingDB Entry DOI: 10.7270/Q24X57X2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP1 Receptor (Mus musculus (Mouse)) | BDBM50308905 (3-[2-({[3-Methyl-1-(1-naphthyl)butyl]amino}carbony...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells by liquid scintillation counting | Bioorg Med Chem 18: 80-90 (2010) Article DOI: 10.1016/j.bmc.2009.11.023 BindingDB Entry DOI: 10.7270/Q24X57X2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP3 Receptor (Mus musculus (Mouse)) | BDBM50308905 (3-[2-({[3-Methyl-1-(1-naphthyl)butyl]amino}carbony...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ... | Bioorg Med Chem 18: 80-90 (2010) Article DOI: 10.1016/j.bmc.2009.11.023 BindingDB Entry DOI: 10.7270/Q24X57X2 | |||||||||||
More data for this Ligand-Target Pair |