BDBM50309173 (1S,2S)-2-(4-benzylpiperazin-1-yl)-1-(5-chloro-6-methoxynaphthalen-2-yl)propan-1-ol::CHEMBL591912::rac-erythro-2-(4-benzylpiperazin-1-yl)-1-(5-chloro-6-methoxynaphthalen-2-yl)propan-1-ol

SMILES: COc1ccc2cc(ccc2c1Cl)[C@H](O)[C@H](C)N1CCN(Cc2ccccc2)CC1

InChI Key: InChIKey=ZCAQYJBALMKXDC-AVRWGWEMSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50309173   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50309173 ((1S,2S)-2-(4-benzylpiperazin-1-yl)-1-(5-chloro-6-m...) Show SMILES COc1ccc2cc(ccc2c1Cl)[C@H](O)[C@H](C)N1CCN(Cc2ccccc2)CC1 |r| Show InChI InChI=1S/C25H29ClN2O2/c1-18(28-14-12-27(13-15-28)17-19-6-4-3-5-7-19)25(29)21-8-10-22-20(16-21)9-11-23(30-2)24(22)26/h3-11,16,18,25,29H,12-15,17H2,1-2H3/t18-,25+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmaceutical Industry Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine reuptake at rat brain frontal cortex dopamine transporter				Bioorg Med Chem Lett 20: 1256-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.108 BindingDB Entry DOI: 10.7270/Q26T0MR2
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50309173 ((1S,2S)-2-(4-benzylpiperazin-1-yl)-1-(5-chloro-6-m...) Show SMILES COc1ccc2cc(ccc2c1Cl)[C@H](O)[C@H](C)N1CCN(Cc2ccccc2)CC1 |r| Show InChI InChI=1S/C25H29ClN2O2/c1-18(28-14-12-27(13-15-28)17-19-6-4-3-5-7-19)25(29)21-8-10-22-20(16-21)9-11-23(30-2)24(22)26/h3-11,16,18,25,29H,12-15,17H2,1-2H3/t18-,25+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	825	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmaceutical Industry Curated by ChEMBL					Assay Description Inhibition of [3H]5HT reuptake at rat brain frontal cortex serotonin transporter				Bioorg Med Chem Lett 20: 1256-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.108 BindingDB Entry DOI: 10.7270/Q26T0MR2
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus (rat))	BDBM50309173 ((1S,2S)-2-(4-benzylpiperazin-1-yl)-1-(5-chloro-6-m...) Show SMILES COc1ccc2cc(ccc2c1Cl)[C@H](O)[C@H](C)N1CCN(Cc2ccccc2)CC1 |r| Show InChI InChI=1S/C25H29ClN2O2/c1-18(28-14-12-27(13-15-28)17-19-6-4-3-5-7-19)25(29)21-8-10-22-20(16-21)9-11-23(30-2)24(22)26/h3-11,16,18,25,29H,12-15,17H2,1-2H3/t18-,25+/m0/s1	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	425	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmaceutical Industry Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine reuptake at rat brain frontal cortex norepinephrine transporter				Bioorg Med Chem Lett 20: 1256-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.108 BindingDB Entry DOI: 10.7270/Q26T0MR2
					More data for this Ligand-Target Pair