BDBM50309186 4-(2-Amino-5-(3-(2-methoxyethoxy)phenyl)pyridin-3-yl)benzamide::CHEMBL592784

SMILES: COCCOc1cccc(c1)-c1cnc(N)c(c1)-c1ccc(cc1)C(N)=O

InChI Key: InChIKey=WIJGRSUJTVWSLD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309186   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50309186 (4-(2-Amino-5-(3-(2-methoxyethoxy)phenyl)pyridin-3-...) Show SMILES COCCOc1cccc(c1)-c1cnc(N)c(c1)-c1ccc(cc1)C(N)=O Show InChI InChI=1S/C21H21N3O3/c1-26-9-10-27-18-4-2-3-16(11-18)17-12-19(20(22)24-13-17)14-5-7-15(8-6-14)21(23)25/h2-8,11-13H,9-10H2,1H3,(H2,22,24)(H2,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 in human HT29 cells				Bioorg Med Chem 18: 707-18 (2010) Article DOI: 10.1016/j.bmc.2009.11.058 BindingDB Entry DOI: 10.7270/Q26974J2
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50309186 (4-(2-Amino-5-(3-(2-methoxyethoxy)phenyl)pyridin-3-...) Show SMILES COCCOc1cccc(c1)-c1cnc(N)c(c1)-c1ccc(cc1)C(N)=O Show InChI InChI=1S/C21H21N3O3/c1-26-9-10-27-18-4-2-3-16(11-18)17-12-19(20(22)24-13-17)14-5-7-15(8-6-14)21(23)25/h2-8,11-13H,9-10H2,1H3,(H2,22,24)(H2,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK1 by DELFIA assay				Bioorg Med Chem 18: 707-18 (2010) Article DOI: 10.1016/j.bmc.2009.11.058 BindingDB Entry DOI: 10.7270/Q26974J2
					More data for this Ligand-Target Pair