BDBM50309258 2-(2-(1-acetyl-4-phenylpiperidin-4-yl)-4-(4-chlorophenyl)thiazol-5-yl)acetic acid::CHEMBL591983

SMILES: CC(=O)N1CCC(CC1)(c1nc(c(CC(O)=O)s1)-c1ccc(Cl)cc1)c1ccccc1

InChI Key: InChIKey=KCGZQDCIVWKSRJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309258   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50309258 (2-(2-(1-acetyl-4-phenylpiperidin-4-yl)-4-(4-chloro...) Show SMILES CC(=O)N1CCC(CC1)(c1nc(c(CC(O)=O)s1)-c1ccc(Cl)cc1)c1ccccc1 Show InChI InChI=1S/C24H23ClN2O3S/c1-16(28)27-13-11-24(12-14-27,18-5-3-2-4-6-18)23-26-22(20(31-23)15-21(29)30)17-7-9-19(25)10-8-17/h2-10H,11-15H2,1H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of[3H]PGD2 from human CRTH2 receptor expressed in HEK385-7 cells				Bioorg Med Chem Lett 20: 1181-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.015 BindingDB Entry DOI: 10.7270/Q2PR7W35
					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50309258 (2-(2-(1-acetyl-4-phenylpiperidin-4-yl)-4-(4-chloro...) Show SMILES CC(=O)N1CCC(CC1)(c1nc(c(CC(O)=O)s1)-c1ccc(Cl)cc1)c1ccccc1 Show InChI InChI=1S/C24H23ClN2O3S/c1-16(28)27-13-11-24(12-14-27,18-5-3-2-4-6-18)23-26-22(20(31-23)15-21(29)30)17-7-9-19(25)10-8-17/h2-10H,11-15H2,1H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in HEK285-7 cells assessed as inhibition of beta arrestin translocation by bioluminescence reso...				Bioorg Med Chem Lett 20: 1181-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.015 BindingDB Entry DOI: 10.7270/Q2PR7W35
					More data for this Ligand-Target Pair