BDBM50309298 2-(2-(bis(4-fluorophenyl)methyl)-4-(3,4-difluorophenyl)thiazol-5-yl)acetic acid::CHEMBL598127

SMILES: OC(=O)Cc1sc(nc1-c1ccc(F)c(F)c1)C(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key: InChIKey=PMKHRUSPKPZZRI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309298   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50309298 (2-(2-(bis(4-fluorophenyl)methyl)-4-(3,4-difluoroph...) Show SMILES OC(=O)Cc1sc(nc1-c1ccc(F)c(F)c1)C(c1ccc(F)cc1)c1ccc(F)cc1 Show InChI InChI=1S/C24H15F4NO2S/c25-16-6-1-13(2-7-16)22(14-3-8-17(26)9-4-14)24-29-23(20(32-24)12-21(30)31)15-5-10-18(27)19(28)11-15/h1-11,22H,12H2,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human CRTH2 receptor expressed in HEK285-7 cells assessed as inhibition of beta arrestin translocation by bioluminescence reso...				Bioorg Med Chem Lett 20: 1181-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.015 BindingDB Entry DOI: 10.7270/Q2PR7W35
					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50309298 (2-(2-(bis(4-fluorophenyl)methyl)-4-(3,4-difluoroph...) Show SMILES OC(=O)Cc1sc(nc1-c1ccc(F)c(F)c1)C(c1ccc(F)cc1)c1ccc(F)cc1 Show InChI InChI=1S/C24H15F4NO2S/c25-16-6-1-13(2-7-16)22(14-3-8-17(26)9-4-14)24-29-23(20(32-24)12-21(30)31)15-5-10-18(27)19(28)11-15/h1-11,22H,12H2,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of[3H]PGD2 from human CRTH2 receptor expressed in HEK385-7 cells				Bioorg Med Chem Lett 20: 1181-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.015 BindingDB Entry DOI: 10.7270/Q2PR7W35
					More data for this Ligand-Target Pair