BDBM50309450 2-(2,4-bis(4-methoxyphenyl)thiazol-5-yl)acetic acid::CHEMBL600245

SMILES: COc1ccc(cc1)-c1nc(c(CC(O)=O)s1)-c1ccc(OC)cc1

InChI Key: InChIKey=WRJKYGUBCWICIK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50309450   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50309450 (2-(2,4-bis(4-methoxyphenyl)thiazol-5-yl)acetic aci...) Show SMILES COc1ccc(cc1)-c1nc(c(CC(O)=O)s1)-c1ccc(OC)cc1 Show InChI InChI=1S/C19H17NO4S/c1-23-14-7-3-12(4-8-14)18-16(11-17(21)22)25-19(20-18)13-5-9-15(24-2)10-6-13/h3-10H,11H2,1-2H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of[3H]PGD2 from human CRTH2 receptor expressed in african green monkey COS7 cells				Bioorg Med Chem Lett 20: 1177-80 (2010) Article DOI: 10.1016/j.bmcl.2009.12.008 BindingDB Entry DOI: 10.7270/Q25T3KMP
					More data for this Ligand-Target Pair