null
SMILES: COc1cc2[nH]cc(C(=O)C(=O)N(C)C)c2cc1C(=O)N1CCC(Cc2ccc(F)cc2)CC1
InChI Key: InChIKey=JQFIEFLOCHABIC-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50309525 (2-(5-(4-(4-fluorobenzyl)piperidine-1-carbonyl)-6-m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Scios Inc. Curated by ChEMBL | Assay Description Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counter | Bioorg Med Chem Lett 20: 2556-9 (2010) Article DOI: 10.1016/j.bmcl.2010.02.088 BindingDB Entry DOI: 10.7270/Q2VT1S84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50309525 (2-(5-(4-(4-fluorobenzyl)piperidine-1-carbonyl)-6-m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Scios, Inc Curated by ChEMBL | Assay Description Inhibition of human p38alpha after 60 mins | Bioorg Med Chem Lett 20: 1059-62 (2010) Article DOI: 10.1016/j.bmcl.2009.12.031 BindingDB Entry DOI: 10.7270/Q2J38SP4 | |||||||||||
More data for this Ligand-Target Pair |