BDBM50309777 5-(2-(dimethylamino)ethylamino)-6H-[1,2,3]triazolo[4,5,1-de]acridin-6-one N-oxide::CHEMBL597442
SMILES: C[N+](C)([O-])CCNc1ccc2nnn3c2c1c(=O)c1ccccc31
InChI Key: InChIKey=DRRKWTDLCSUFQB-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human)) | BDBM50309777 (5-(2-(dimethylamino)ethylamino)-6H-[1,2,3]triazolo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center Curated by ChEMBL | Assay Description Inhibition of human recombinant NQO1 by spectrophotometry | Bioorg Med Chem 18: 696-706 (2010) Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosyldihydronicotinamide dehydrogenase [quinone] (Homo sapiens (Human)) | BDBM50309777 (5-(2-(dimethylamino)ethylamino)-6H-[1,2,3]triazolo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 167 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester and Manchester Cancer Research Center Curated by ChEMBL | Assay Description Inhibition of human recombinant NQO2 by spectrophotometry | Bioorg Med Chem 18: 696-706 (2010) Article DOI: 10.1016/j.bmc.2009.11.059 BindingDB Entry DOI: 10.7270/Q2CC10TZ | |||||||||||
More data for this Ligand-Target Pair |