BDBM50309833 (S)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide::CHEMBL597477

SMILES: NC(=O)[C@H]1CCCc2c1[nH]c1ccc(Cl)cc21

InChI Key: InChIKey=FUZYTVDVLBBXDL-VIFPVBQESA-N

Data: 2 IC50

PDB links: 6 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309833   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human))	BDBM50309833 ((S)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-car...) Show SMILES NC(=O)[C@H]1CCCc2c1[nH]c1ccc(Cl)cc21 |r| Show InChI InChI=1S/C13H13ClN2O/c14-7-4-5-11-10(6-7)8-2-1-3-9(13(15)17)12(8)16-11/h4-6,9,16H,1-3H2,(H2,15,17)/t9-/m0/s1	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT2 by Flour de Lys assay				J Med Chem 53: 1407-11 (2010) Article DOI: 10.1021/jm9013345 BindingDB Entry DOI: 10.7270/Q23T9HBX
					More data for this Ligand-Target Pair				3D Structure (crystal)
NAD-Dependent Deacetylase Sirtuin-1 (Homo sapiens (Human))	BDBM50309833 ((S)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-car...) Show SMILES NC(=O)[C@H]1CCCc2c1[nH]c1ccc(Cl)cc21 |r| Show InChI InChI=1S/C13H13ClN2O/c14-7-4-5-11-10(6-7)8-2-1-3-9(13(15)17)12(8)16-11/h4-6,9,16H,1-3H2,(H2,15,17)/t9-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT1 by Flour de Lys assay				J Med Chem 53: 1407-11 (2010) Article DOI: 10.1021/jm9013345 BindingDB Entry DOI: 10.7270/Q23T9HBX
					More data for this Ligand-Target Pair