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BDBM50309871 4-Oxazolo[5,4-b]pyridin-2-yl-1,4-diazabicyclo[3.2.2]nonane::CHEMBL605715

SMILES: C1CN2CCC1N(CC2)c1nc2cccnc2o1

InChI Key: InChIKey=DNBUHXJXKUSPHI-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309871   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50309871
PNG
(4-Oxazolo[5,4-b]pyridin-2-yl-1,4-diazabicyclo[3.2....)
Show SMILES C1CN2CCC1N(CC2)c1nc2cccnc2o1
Show InChI InChI=1S/C13H16N4O/c1-2-11-12(14-5-1)18-13(15-11)17-9-8-16-6-3-10(17)4-7-16/h1-2,5,10H,3-4,6-9H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
40.6n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells


J Med Chem 53: 1222-37 (2010)

More data for this
Ligand-Target Pair
5-HT3A Serotonin Receptor


(Mus musculus (house mouse))
BDBM50309871
PNG
(4-Oxazolo[5,4-b]pyridin-2-yl-1,4-diazabicyclo[3.2....)
Show SMILES C1CN2CCC1N(CC2)c1nc2cccnc2o1
Show InChI InChI=1S/C13H16N4O/c1-2-11-12(14-5-1)18-13(15-11)17-9-8-16-6-3-10(17)4-7-16/h1-2,5,10H,3-4,6-9H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
92n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cells


J Med Chem 53: 1222-37 (2010)

More data for this
Ligand-Target Pair