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BDBM50309976 4-((1H-1,2,4-triazol-1-yl)methyl)-5-(4-chlorophenyl)-N-cyclopentyl-1-(2,4-dichlorophenyl)-1H-pyrazole-3-carboxamide::CHEMBL597679

SMILES: Clc1ccc(cc1)-c1c(Cn2cncn2)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NC1CCCC1

InChI Key: InChIKey=YPYAVTIMRWXDIE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50309976   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309976
PNG
(4-((1H-1,2,4-triazol-1-yl)methyl)-5-(4-chloropheny...)
Show SMILES Clc1ccc(cc1)-c1c(Cn2cncn2)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NC1CCCC1
Show InChI InChI=1S/C24H21Cl3N6O/c25-16-7-5-15(6-8-16)23-19(12-32-14-28-13-29-32)22(24(34)30-18-3-1-2-4-18)31-33(23)21-10-9-17(26)11-20(21)27/h5-11,13-14,18H,1-4,12H2,(H,30,34)
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.90n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair