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BDBM50310049 4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-N-(1-(trifluoromethyl)cyclopropyl)-1Hpyrazole-3-carboxamide::CHEMBL599372

SMILES: FC(F)(F)C1(CC1)NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=XEIHMXADOVQJHK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310049   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310049
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES FC(F)(F)C1(CC1)NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C23H16BrCl2F3N6O/c24-14-3-1-13(2-4-14)20-16(10-34-12-30-11-31-34)19(21(36)32-22(7-8-22)23(27,28)29)33-35(20)18-6-5-15(25)9-17(18)26/h1-6,9,11-12H,7-8,10H2,(H,32,36)
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.31n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair