BDBM50310218 7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphenyl)-2-phenylpyrazolo[1,5-a]pyrimidine::CHEMBL604940

SMILES: FC(F)Oc1ccc(cc1OCC1CC1)-c1ccnc2cc(nn12)-c1ccccc1

InChI Key: InChIKey=YTHDHWAAWWAEPI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310218   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50310218 (7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphenyl)...) Show SMILES FC(F)Oc1ccc(cc1OCC1CC1)-c1ccnc2cc(nn12)-c1ccccc1 Show InChI InChI=1S/C23H19F2N3O2/c24-23(25)30-20-9-8-17(12-21(20)29-14-15-6-7-15)19-10-11-26-22-13-18(27-28(19)22)16-4-2-1-3-5-16/h1-5,8-13,15,23H,6-7,14H2	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of human PDE4D				Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S
					More data for this Ligand-Target Pair