null

SMILES: CCN(CC)CCOc1ccc(cc1)[C@H]1Oc2cc(F)ccc2C2=C1c1ccc(O)cc1OCC2

InChI Key: InChIKey=FEVNXNWGPTZNEC-GDLZYMKVSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50310410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor beta (Homo sapiens (Human))	BDBM50310410 ((R)-5-[4-(2-Diethylamino-ethoxy)-phenyl]-8-fluoro-...) Show SMILES CCN(CC)CCOc1ccc(cc1)[C@H]1Oc2cc(F)ccc2C2=C1c1ccc(O)cc1OCC2 |r,c:25| Show InChI InChI=1S/C29H30FNO4/c1-3-31(4-2)14-16-33-22-9-5-19(6-10-22)29-28-24(23-11-7-20(30)17-27(23)35-29)13-15-34-26-18-21(32)8-12-25(26)28/h5-12,17-18,29,32H,3-4,13-16H2,1-2H3/t29-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of fluormone ES2 binding to estrogen receptor beta after 1 hr by fluorescence polarization assay				J Med Chem 52: 7544-69 (2009) Article DOI: 10.1021/jm900146e BindingDB Entry DOI: 10.7270/Q27D2V8M
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50310410 ((R)-5-[4-(2-Diethylamino-ethoxy)-phenyl]-8-fluoro-...) Show SMILES CCN(CC)CCOc1ccc(cc1)[C@H]1Oc2cc(F)ccc2C2=C1c1ccc(O)cc1OCC2 |r,c:25| Show InChI InChI=1S/C29H30FNO4/c1-3-31(4-2)14-16-33-22-9-5-19(6-10-22)29-28-24(23-11-7-20(30)17-27(23)35-29)13-15-34-26-18-21(32)8-12-25(26)28/h5-12,17-18,29,32H,3-4,13-16H2,1-2H3/t29-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor in human MCF7 cells assessed as 17beta-estradiol-induced cell proliferation after 24 hrs by [14C]thymidine i...				J Med Chem 52: 7544-69 (2009) Article DOI: 10.1021/jm900146e BindingDB Entry DOI: 10.7270/Q27D2V8M
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50310410 ((R)-5-[4-(2-Diethylamino-ethoxy)-phenyl]-8-fluoro-...) Show SMILES CCN(CC)CCOc1ccc(cc1)[C@H]1Oc2cc(F)ccc2C2=C1c1ccc(O)cc1OCC2 |r,c:25| Show InChI InChI=1S/C29H30FNO4/c1-3-31(4-2)14-16-33-22-9-5-19(6-10-22)29-28-24(23-11-7-20(30)17-27(23)35-29)13-15-34-26-18-21(32)8-12-25(26)28/h5-12,17-18,29,32H,3-4,13-16H2,1-2H3/t29-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	113	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor in human Ishikawa cells assessed as 17beta-estradiol-induced alkaline phosphatase activity after 3 days by c...				J Med Chem 52: 7544-69 (2009) Article DOI: 10.1021/jm900146e BindingDB Entry DOI: 10.7270/Q27D2V8M
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50310410 ((R)-5-[4-(2-Diethylamino-ethoxy)-phenyl]-8-fluoro-...) Show SMILES CCN(CC)CCOc1ccc(cc1)[C@H]1Oc2cc(F)ccc2C2=C1c1ccc(O)cc1OCC2 |r,c:25| Show InChI InChI=1S/C29H30FNO4/c1-3-31(4-2)14-16-33-22-9-5-19(6-10-22)29-28-24(23-11-7-20(30)17-27(23)35-29)13-15-34-26-18-21(32)8-12-25(26)28/h5-12,17-18,29,32H,3-4,13-16H2,1-2H3/t29-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Displacement of radiolabeled estrogen from estrogen receptor alpha by scintillation counting				J Med Chem 52: 7544-69 (2009) Article DOI: 10.1021/jm900146e BindingDB Entry DOI: 10.7270/Q27D2V8M
					More data for this Ligand-Target Pair