BDBM50310611 CHEMBL1079052::N-(4-(1-methyl-1H-benzo[d]imidazol-2-ylamino)phenethyl)thieno[3,2-d]pyrimidin-4-amine

SMILES: Cn1c(Nc2ccc(CCNc3ncnc4ccsc34)cc2)nc2ccccc12

InChI Key: InChIKey=KEOVIOTXXBEWRT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310611   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM50310611 (CHEMBL1079052 | N-(4-(1-methyl-1H-benzo[d]imidazol...) Show SMILES Cn1c(Nc2ccc(CCNc3ncnc4ccsc34)cc2)nc2ccccc12 Show InChI InChI=1S/C22H20N6S/c1-28-19-5-3-2-4-17(19)27-22(28)26-16-8-6-15(7-9-16)10-12-23-21-20-18(11-13-29-20)24-14-25-21/h2-9,11,13-14H,10,12H2,1H3,(H,26,27)(H,23,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B after 60 mins				Bioorg Med Chem Lett 19: 5158-61 (2009) Article DOI: 10.1016/j.bmcl.2009.07.016 BindingDB Entry DOI: 10.7270/Q2T72HK2
					More data for this Ligand-Target Pair