BDBM50310624 CHEMBL1081881::N-(2-(6-(5-(trifluoromethyl)-1H-benzo[d]imidazol-2-ylamino)pyridin-3-yl)ethyl)thieno[3,2-d]pyrimidin-4-amine

SMILES: FC(F)(F)c1ccc2nc(Nc3ccc(CCNc4ncnc5ccsc45)cn3)[nH]c2c1

InChI Key: InChIKey=RTLVOQTYFNGFIY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310624   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM50310624 (CHEMBL1081881 | N-(2-(6-(5-(trifluoromethyl)-1H-be...) Show SMILES FC(F)(F)c1ccc2nc(Nc3ccc(CCNc4ncnc5ccsc45)cn3)[nH]c2c1 Show InChI InChI=1S/C21H16F3N7S/c22-21(23,24)13-2-3-14-16(9-13)30-20(29-14)31-17-4-1-12(10-26-17)5-7-25-19-18-15(6-8-32-18)27-11-28-19/h1-4,6,8-11H,5,7H2,(H,25,27,28)(H2,26,29,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B after 60 mins				Bioorg Med Chem Lett 19: 5158-61 (2009) Article DOI: 10.1016/j.bmcl.2009.07.016 BindingDB Entry DOI: 10.7270/Q2T72HK2
					More data for this Ligand-Target Pair