BDBM50310640 4-(3-(5-tert-butylisoxazol-3-yl)ureido)-N-phenylbenzamide::CHEMBL1081510

SMILES: CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)C(=O)Nc2ccccc2)no1

InChI Key: InChIKey=KXJGDQGCCWDCED-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310640   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50310640 (4-(3-(5-tert-butylisoxazol-3-yl)ureido)-N-phenylbe...) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)C(=O)Nc2ccccc2)no1 Show InChI InChI=1S/C21H22N4O3/c1-21(2,3)17-13-18(25-28-17)24-20(27)23-16-11-9-14(10-12-16)19(26)22-15-7-5-4-6-8-15/h4-13H,1-3H3,(H,22,26)(H2,23,24,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Inc. Curated by ChEMBL					Assay Description Binding affinity to FLT3				Bioorg Med Chem Lett 19: 5182-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.024 BindingDB Entry DOI: 10.7270/Q2PG1RVB
					More data for this Ligand-Target Pair