BDBM50310643 4-(3-(5-tert-butylisoxazol-3-yl)ureido)-N-(pyridin-4-yl)benzamide::CHEMBL1080784

SMILES: CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)C(=O)Nc2ccncc2)no1

InChI Key: InChIKey=RXQKYRGFBQTLGW-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310643   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50310643 (4-(3-(5-tert-butylisoxazol-3-yl)ureido)-N-(pyridin...) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)C(=O)Nc2ccncc2)no1 Show InChI InChI=1S/C20H21N5O3/c1-20(2,3)16-12-17(25-28-16)24-19(27)23-14-6-4-13(5-7-14)18(26)22-15-8-10-21-11-9-15/h4-12H,1-3H3,(H,21,22,26)(H2,23,24,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	38.4	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Inc. Curated by ChEMBL					Assay Description Binding affinity to FLT3				Bioorg Med Chem Lett 19: 5182-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.024 BindingDB Entry DOI: 10.7270/Q2PG1RVB
					More data for this Ligand-Target Pair