BDBM50310787 CHEMBL1079360::N-(4-chlorophenyl)-3-methyl-3-phenylpiperidine-1-carboxamide

SMILES: CC1(CCCN(C1)C(=O)Nc1ccc(Cl)cc1)c1ccccc1

InChI Key: InChIKey=KXYUVZFKXATOCP-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50310787   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50310787 (CHEMBL1079360 | N-(4-chlorophenyl)-3-methyl-3-phen...) Show SMILES CC1(CCCN(C1)C(=O)Nc1ccc(Cl)cc1)c1ccccc1 Show InChI InChI=1S/C19H21ClN2O/c1-19(15-6-3-2-4-7-15)12-5-13-22(14-19)18(23)21-17-10-8-16(20)9-11-17/h2-4,6-11H,5,12-14H2,1H3,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 19: 5314-20 (2009) Article DOI: 10.1016/j.bmcl.2009.07.138 BindingDB Entry DOI: 10.7270/Q2S75GFP
					More data for this Ligand-Target Pair
Epoxide hydrolase 2 (Rattus norvegicus)	BDBM50310787 (CHEMBL1079360 | N-(4-chlorophenyl)-3-methyl-3-phen...) Show SMILES CC1(CCCN(C1)C(=O)Nc1ccc(Cl)cc1)c1ccccc1 Show InChI InChI=1S/C19H21ClN2O/c1-19(15-6-3-2-4-7-15)12-5-13-22(14-19)18(23)21-17-10-8-16(20)9-11-17/h2-4,6-11H,5,12-14H2,1H3,(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of rat soluble epoxide hydrolase				Bioorg Med Chem Lett 19: 5314-20 (2009) Article DOI: 10.1016/j.bmcl.2009.07.138 BindingDB Entry DOI: 10.7270/Q2S75GFP
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50310787 (CHEMBL1079360 | N-(4-chlorophenyl)-3-methyl-3-phen...) Show SMILES CC1(CCCN(C1)C(=O)Nc1ccc(Cl)cc1)c1ccccc1 Show InChI InChI=1S/C19H21ClN2O/c1-19(15-6-3-2-4-7-15)12-5-13-22(14-19)18(23)21-17-10-8-16(20)9-11-17/h2-4,6-11H,5,12-14H2,1H3,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Nav1.5 channel				Bioorg Med Chem Lett 19: 5314-20 (2009) Article DOI: 10.1016/j.bmcl.2009.07.138 BindingDB Entry DOI: 10.7270/Q2S75GFP
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50310787 (CHEMBL1079360 | N-(4-chlorophenyl)-3-methyl-3-phen...) Show SMILES CC1(CCCN(C1)C(=O)Nc1ccc(Cl)cc1)c1ccccc1 Show InChI InChI=1S/C19H21ClN2O/c1-19(15-6-3-2-4-7-15)12-5-13-22(14-19)18(23)21-17-10-8-16(20)9-11-17/h2-4,6-11H,5,12-14H2,1H3,(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CYP2C9				Bioorg Med Chem Lett 19: 5314-20 (2009) Article DOI: 10.1016/j.bmcl.2009.07.138 BindingDB Entry DOI: 10.7270/Q2S75GFP
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50310787 (CHEMBL1079360 | N-(4-chlorophenyl)-3-methyl-3-phen...) Show SMILES CC1(CCCN(C1)C(=O)Nc1ccc(Cl)cc1)c1ccccc1 Show InChI InChI=1S/C19H21ClN2O/c1-19(15-6-3-2-4-7-15)12-5-13-22(14-19)18(23)21-17-10-8-16(20)9-11-17/h2-4,6-11H,5,12-14H2,1H3,(H,21,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CYP2D6				Bioorg Med Chem Lett 19: 5314-20 (2009) Article DOI: 10.1016/j.bmcl.2009.07.138 BindingDB Entry DOI: 10.7270/Q2S75GFP
					More data for this Ligand-Target Pair
Epoxide hydrolase 1 (Homo sapiens (Human))	BDBM50310787 (CHEMBL1079360 | N-(4-chlorophenyl)-3-methyl-3-phen...) Show SMILES CC1(CCCN(C1)C(=O)Nc1ccc(Cl)cc1)c1ccccc1 Show InChI InChI=1S/C19H21ClN2O/c1-19(15-6-3-2-4-7-15)12-5-13-22(14-19)18(23)21-17-10-8-16(20)9-11-17/h2-4,6-11H,5,12-14H2,1H3,(H,21,23)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human microsomal epoxide hydrolase				Bioorg Med Chem Lett 19: 5314-20 (2009) Article DOI: 10.1016/j.bmcl.2009.07.138 BindingDB Entry DOI: 10.7270/Q2S75GFP
					More data for this Ligand-Target Pair