BDBM50310884 CHEMBL1078502::N,N'-(9-(cycloheptylamino)acridine-3,6-diyl)bis(3-(pyrrolidin-1-yl)propanamide)

SMILES: O=C(CCN1CCCC1)Nc1ccc2c(NC3CCCCCC3)c3ccc(NC(=O)CCN4CCCC4)cc3nc2c1

InChI Key: InChIKey=YMXRYBNAQKQXFU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310884   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50310884 (CHEMBL1078502 | N,N'-(9-(cycloheptylamino)acridine...) Show SMILES O=C(CCN1CCCC1)Nc1ccc2c(NC3CCCCCC3)c3ccc(NC(=O)CCN4CCCC4)cc3nc2c1 Show InChI InChI=1S/C34H46N6O2/c41-32(15-21-39-17-5-6-18-39)35-26-11-13-28-30(23-26)38-31-24-27(36-33(42)16-22-40-19-7-8-20-40)12-14-29(31)34(28)37-25-9-3-1-2-4-10-25/h11-14,23-25H,1-10,15-22H2,(H,35,41)(H,36,42)(H,37,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Central University of Las Villas Curated by ChEMBL					Assay Description Inhibition of telomerase in human A2780 cells by TRAP assay				Eur J Med Chem 44: 4826-40 (2009) Article DOI: 10.1016/j.ejmech.2009.07.029 BindingDB Entry DOI: 10.7270/Q20R9PHM
					More data for this Ligand-Target Pair