BDBM50310986 CHEMBL1078667::N-(4-((3-chloro-4-(2,4-difluorobenzyloxy)-6-methyl-2-oxopyridin-1(2H)-yl)methyl)benzyl)-2-hydroxyacetamide

SMILES: Cc1cc(OCc2ccc(F)cc2F)c(Cl)c(=O)n1Cc1ccc(CNC(=O)CO)cc1

InChI Key: InChIKey=MZXAVKHTGQDLOY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50310986   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50310986 (CHEMBL1078667 | N-(4-((3-chloro-4-(2,4-difluoroben...) Show SMILES Cc1cc(OCc2ccc(F)cc2F)c(Cl)c(=O)n1Cc1ccc(CNC(=O)CO)cc1 Show InChI InChI=1S/C23H21ClF2N2O4/c1-14-8-20(32-13-17-6-7-18(25)9-19(17)26)22(24)23(31)28(14)11-16-4-2-15(3-5-16)10-27-21(30)12-29/h2-9,29H,10-13H2,1H3,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Corporation Curated by ChEMBL					Assay Description Inhibition of JNK2				Bioorg Med Chem Lett 19: 5851-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.082 BindingDB Entry DOI: 10.7270/Q2HM59DG
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50310986 (CHEMBL1078667 | N-(4-((3-chloro-4-(2,4-difluoroben...) Show SMILES Cc1cc(OCc2ccc(F)cc2F)c(Cl)c(=O)n1Cc1ccc(CNC(=O)CO)cc1 Show InChI InChI=1S/C23H21ClF2N2O4/c1-14-8-20(32-13-17-6-7-18(25)9-19(17)26)22(24)23(31)28(14)11-16-4-2-15(3-5-16)10-27-21(30)12-29/h2-9,29H,10-13H2,1H3,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Corporation Curated by ChEMBL					Assay Description Inhibition of p38alpha				Bioorg Med Chem Lett 19: 5851-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.082 BindingDB Entry DOI: 10.7270/Q2HM59DG
					More data for this Ligand-Target Pair