BDBM50311091 CHEMBL1078322::rac-1-(5-(4-chloro-1H-pyrazol-1-yl)thiophene-2-sulfonamido)-2,3-dimethylcyclopropanecarboxylic acid

SMILES: C[C@H]1[C@@H](C)[C@@]1(NS(=O)(=O)c1ccc(s1)-n1cc(Cl)cn1)C(O)=O

InChI Key: InChIKey=JDSLPJPAJIWLER-BWPRHRIFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50311091   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) (Homo sapiens (Human))	BDBM50311091 (CHEMBL1078322 | rac-1-(5-(4-chloro-1H-pyrazol-1-yl...) Show SMILES C[C@H]1[C@@H](C)[C@@]1(NS(=O)(=O)c1ccc(s1)-n1cc(Cl)cn1)C(O)=O |r| Show InChI InChI=1S/C13H14ClN3O4S2/c1-7-8(2)13(7,12(18)19)16-23(20,21)11-4-3-10(22-11)17-6-9(14)5-15-17/h3-8,16H,1-2H3,(H,18,19)/t7-,8+,13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of ADAMTS5				Bioorg Med Chem Lett 19: 6213-7 (2009) Article DOI: 10.1016/j.bmcl.2009.08.093 BindingDB Entry DOI: 10.7270/Q2ZS2WMT
					More data for this Ligand-Target Pair