null

SMILES: CN(C)CCNC(=O)c1ccc2OCC(Cc2c1)c1nc2ccc(cc2s1)-c1cn[nH]c1

InChI Key: InChIKey=DOVACETXYXXOTL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311724   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50311724 (3-(6-(1H-pyrazol-4-yl)benzo[d]thiazol-2-yl)-N-(2-(...) Show SMILES CN(C)CCNC(=O)c1ccc2OCC(Cc2c1)c1nc2ccc(cc2s1)-c1cn[nH]c1 Show InChI InChI=1S/C24H25N5O2S/c1-29(2)8-7-25-23(30)16-4-6-21-17(9-16)10-18(14-31-21)24-28-20-5-3-15(11-22(20)32-24)19-12-26-27-13-19/h3-6,9,11-13,18H,7-8,10,14H2,1-2H3,(H,25,30)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute and Department of Molecular Therapeutics Curated by ChEMBL					Assay Description Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assay				Bioorg Med Chem Lett 19: 6686-90 (2009) Article DOI: 10.1016/j.bmcl.2009.09.115 BindingDB Entry DOI: 10.7270/Q2VX0GN0
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50311724 (3-(6-(1H-pyrazol-4-yl)benzo[d]thiazol-2-yl)-N-(2-(...) Show SMILES CN(C)CCNC(=O)c1ccc2OCC(Cc2c1)c1nc2ccc(cc2s1)-c1cn[nH]c1 Show InChI InChI=1S/C24H25N5O2S/c1-29(2)8-7-25-23(30)16-4-6-21-17(9-16)10-18(14-31-21)24-28-20-5-3-15(11-22(20)32-24)19-12-26-27-13-19/h3-6,9,11-13,18H,7-8,10,14H2,1-2H3,(H,25,30)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute and Department of Molecular Therapeutics Curated by ChEMBL					Assay Description Inhibition of ROCK2				Bioorg Med Chem Lett 19: 6686-90 (2009) Article DOI: 10.1016/j.bmcl.2009.09.115 BindingDB Entry DOI: 10.7270/Q2VX0GN0
					More data for this Ligand-Target Pair