BDBM50311788 4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzamido)methyl)-2-methylbiphenyl-3-carboxylic acid::CHEMBL1081354

SMILES: CCCCOc1ccc(cc1CNC(=O)c1ccc(cc1F)C(F)(F)F)-c1cccc(C(O)=O)c1C

InChI Key: InChIKey=ZQMRWLOZDCPEGS-UHFFFAOYSA-N

Data: 5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50311788   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50311788 (4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...) Show SMILES CCCCOc1ccc(cc1CNC(=O)c1ccc(cc1F)C(F)(F)F)-c1cccc(C(O)=O)c1C Show InChI InChI=1S/C27H25F4NO4/c1-3-4-12-36-24-11-8-17(20-6-5-7-21(16(20)2)26(34)35)13-18(24)15-32-25(33)22-10-9-19(14-23(22)28)27(29,30)31/h5-11,13-14H,3-4,12,15H2,1-2H3,(H,32,33)(H,34,35)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at PPARalpha receptor expressed in HEK293 cells cotransfected with GAL4 by transactivation assay				Bioorg Med Chem Lett 19: 6595-9 (2009) Article DOI: 10.1016/j.bmcl.2009.10.021 BindingDB Entry DOI: 10.7270/Q2736R23
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50311788 (4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...) Show SMILES CCCCOc1ccc(cc1CNC(=O)c1ccc(cc1F)C(F)(F)F)-c1cccc(C(O)=O)c1C Show InChI InChI=1S/C27H25F4NO4/c1-3-4-12-36-24-11-8-17(20-6-5-7-21(16(20)2)26(34)35)13-18(24)15-32-25(33)22-10-9-19(14-23(22)28)27(29,30)31/h5-11,13-14H,3-4,12,15H2,1-2H3,(H,32,33)(H,34,35)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at PPARdelta receptor expressed in HEK293 cells cotransfected with GAL4 by transactivation assay				Bioorg Med Chem Lett 19: 6595-9 (2009) Article DOI: 10.1016/j.bmcl.2009.10.021 BindingDB Entry DOI: 10.7270/Q2736R23
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50311788 (4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...) Show SMILES CCCCOc1ccc(cc1CNC(=O)c1ccc(cc1F)C(F)(F)F)-c1cccc(C(O)=O)c1C Show InChI InChI=1S/C27H25F4NO4/c1-3-4-12-36-24-11-8-17(20-6-5-7-21(16(20)2)26(34)35)13-18(24)15-32-25(33)22-10-9-19(14-23(22)28)27(29,30)31/h5-11,13-14H,3-4,12,15H2,1-2H3,(H,32,33)(H,34,35)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Partial agonist activity at PPARdelta				J Med Chem 54: 1539-54 (2011) Article DOI: 10.1021/jm101356p BindingDB Entry DOI: 10.7270/Q27S7P30
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50311788 (4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...) Show SMILES CCCCOc1ccc(cc1CNC(=O)c1ccc(cc1F)C(F)(F)F)-c1cccc(C(O)=O)c1C Show InChI InChI=1S/C27H25F4NO4/c1-3-4-12-36-24-11-8-17(20-6-5-7-21(16(20)2)26(34)35)13-18(24)15-32-25(33)22-10-9-19(14-23(22)28)27(29,30)31/h5-11,13-14H,3-4,12,15H2,1-2H3,(H,32,33)(H,34,35)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at PPARalpha				J Med Chem 54: 1539-54 (2011) Article DOI: 10.1021/jm101356p BindingDB Entry DOI: 10.7270/Q27S7P30
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50311788 (4'-butoxy-3'-((2-fluoro-4-(trifluoromethyl)benzami...) Show SMILES CCCCOc1ccc(cc1CNC(=O)c1ccc(cc1F)C(F)(F)F)-c1cccc(C(O)=O)c1C Show InChI InChI=1S/C27H25F4NO4/c1-3-4-12-36-24-11-8-17(20-6-5-7-21(16(20)2)26(34)35)13-18(24)15-32-25(33)22-10-9-19(14-23(22)28)27(29,30)31/h5-11,13-14H,3-4,12,15H2,1-2H3,(H,32,33)(H,34,35)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Partial agonist activity at human recombinant PPARdelta LBD expressed in HEK293 cells cotransfected with Gal4 assessed as beta-galactosidase activity...				Bioorg Med Chem 18: 7164-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.041 BindingDB Entry DOI: 10.7270/Q2862GN7
					More data for this Ligand-Target Pair