BDBM50311960 4-(4-methyl-1H-indol-5-ylamino)-5-(4-((4-methylpiperazin-1-ylsulfonyl)methyl)styryl)nicotinonitrile::CHEMBL1081920

SMILES: CN1CCN(CC1)S(=O)(=O)Cc1ccc(\C=C\c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)cc1

InChI Key: InChIKey=PHDOQFYDQFLEMJ-BQYQJAHWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311960   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50311960 (4-(4-methyl-1H-indol-5-ylamino)-5-(4-((4-methylpip...) Show SMILES CN1CCN(CC1)S(=O)(=O)Cc1ccc(\C=C\c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)cc1 Show InChI InChI=1S/C29H30N6O2S/c1-21-26-11-12-32-28(26)10-9-27(21)33-29-24(18-31-19-25(29)17-30)8-7-22-3-5-23(6-4-22)20-38(36,37)35-15-13-34(2)14-16-35/h3-12,18-19,32H,13-16,20H2,1-2H3,(H,31,33)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 19: 6575-7 (2009) Article DOI: 10.1016/j.bmcl.2009.10.031 BindingDB Entry DOI: 10.7270/Q2KD1Z1F
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50311960 (4-(4-methyl-1H-indol-5-ylamino)-5-(4-((4-methylpip...) Show SMILES CN1CCN(CC1)S(=O)(=O)Cc1ccc(\C=C\c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)cc1 Show InChI InChI=1S/C29H30N6O2S/c1-21-26-11-12-32-28(26)10-9-27(21)33-29-24(18-31-19-25(29)17-30)8-7-22-3-5-23(6-4-22)20-38(36,37)35-15-13-34(2)14-16-35/h3-12,18-19,32H,13-16,20H2,1-2H3,(H,31,33)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 19: 6575-7 (2009) Article DOI: 10.1016/j.bmcl.2009.10.031 BindingDB Entry DOI: 10.7270/Q2KD1Z1F
					More data for this Ligand-Target Pair