BDBM50311967 6-(1-methyl-4-phenyl-1H-imidazol-5-yl)thieno[2,3-d]pyrimidin-4-amine::CHEMBL1079428

SMILES: Cn1cnc(c1-c1cc2c(N)ncnc2s1)-c1ccccc1

InChI Key: InChIKey=NTRDNLUCOPAXFK-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50311967   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50311967 (6-(1-methyl-4-phenyl-1H-imidazol-5-yl)thieno[2,3-d...) Show SMILES Cn1cnc(c1-c1cc2c(N)ncnc2s1)-c1ccccc1 Show InChI InChI=1S/C16H13N5S/c1-21-9-20-13(10-5-3-2-4-6-10)14(21)12-7-11-15(17)18-8-19-16(11)22-12/h2-9H,1H3,(H2,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of Tie-2 phosphorylation by cell based assay				Bioorg Med Chem Lett 19: 6670-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.001 BindingDB Entry DOI: 10.7270/Q2FN16BJ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50311967 (6-(1-methyl-4-phenyl-1H-imidazol-5-yl)thieno[2,3-d...) Show SMILES Cn1cnc(c1-c1cc2c(N)ncnc2s1)-c1ccccc1 Show InChI InChI=1S/C16H13N5S/c1-21-9-20-13(10-5-3-2-4-6-10)14(21)12-7-11-15(17)18-8-19-16(11)22-12/h2-9H,1H3,(H2,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of FLt				Bioorg Med Chem Lett 19: 6670-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.001 BindingDB Entry DOI: 10.7270/Q2FN16BJ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50311967 (6-(1-methyl-4-phenyl-1H-imidazol-5-yl)thieno[2,3-d...) Show SMILES Cn1cnc(c1-c1cc2c(N)ncnc2s1)-c1ccccc1 Show InChI InChI=1S/C16H13N5S/c1-21-9-20-13(10-5-3-2-4-6-10)14(21)12-7-11-15(17)18-8-19-16(11)22-12/h2-9H,1H3,(H2,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 19: 6670-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.001 BindingDB Entry DOI: 10.7270/Q2FN16BJ
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50311967 (6-(1-methyl-4-phenyl-1H-imidazol-5-yl)thieno[2,3-d...) Show SMILES Cn1cnc(c1-c1cc2c(N)ncnc2s1)-c1ccccc1 Show InChI InChI=1S/C16H13N5S/c1-21-9-20-13(10-5-3-2-4-6-10)14(21)12-7-11-15(17)18-8-19-16(11)22-12/h2-9H,1H3,(H2,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of Tie-2				Bioorg Med Chem Lett 19: 6670-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.001 BindingDB Entry DOI: 10.7270/Q2FN16BJ
					More data for this Ligand-Target Pair