BDBM50311968 6-(1-methyl-4-(3-(p-tolylthio)phenyl)-1H-imidazol-5-yl)thieno[2,3-d]pyrimidin-4-amine::CHEMBL1079429

SMILES: Cc1ccc(Sc2cccc(c2)-c2ncn(C)c2-c2cc3c(N)ncnc3s2)cc1

InChI Key: InChIKey=XKDIECPVMKTCRQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50311968   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50311968 (6-(1-methyl-4-(3-(p-tolylthio)phenyl)-1H-imidazol-...) Show SMILES Cc1ccc(Sc2cccc(c2)-c2ncn(C)c2-c2cc3c(N)ncnc3s2)cc1 Show InChI InChI=1S/C23H19N5S2/c1-14-6-8-16(9-7-14)29-17-5-3-4-15(10-17)20-21(28(2)13-27-20)19-11-18-22(24)25-12-26-23(18)30-19/h3-13H,1-2H3,(H2,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of Tie-2 phosphorylation by cell based assay				Bioorg Med Chem Lett 19: 6670-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.001 BindingDB Entry DOI: 10.7270/Q2FN16BJ
					More data for this Ligand-Target Pair