BDBM50311969 1-(3-(5-(4-aminothieno[2,3-d]pyrimidin-6-yl)-1-methyl-1H-imidazol-4-yl)phenyl)-3-phenylurea::CHEMBL1080127

SMILES: Cn1cnc(c1-c1cc2c(N)ncnc2s1)-c1cccc(NC(=O)Nc2ccccc2)c1

InChI Key: InChIKey=XENVUQNDKCYZLP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50311969   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50311969 (1-(3-(5-(4-aminothieno[2,3-d]pyrimidin-6-yl)-1-met...) Show SMILES Cn1cnc(c1-c1cc2c(N)ncnc2s1)-c1cccc(NC(=O)Nc2ccccc2)c1 Show InChI InChI=1S/C23H19N7OS/c1-30-13-27-19(20(30)18-11-17-21(24)25-12-26-22(17)32-18)14-6-5-9-16(10-14)29-23(31)28-15-7-3-2-4-8-15/h2-13H,1H3,(H2,24,25,26)(H2,28,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of Tie-2 phosphorylation by cell based assay				Bioorg Med Chem Lett 19: 6670-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.001 BindingDB Entry DOI: 10.7270/Q2FN16BJ
					More data for this Ligand-Target Pair