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BDBM50312032 (+/-)-N-(4-(4-methyl-5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenethyl)benzo[d]thiazol-2-amine::CHEMBL1080291

SMILES: CC1CCSC(N1)=Nc1ccc(CCNc2nc3ccccc3s2)cc1

InChI Key: InChIKey=IZUWEWNGZAVAQH-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312032   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuropeptide Y receptor type 1


(Homo sapiens (Human))
BDBM50312032
PNG
((+/-)-N-(4-(4-methyl-5,6-dihydro-4H-1,3-thiazin-2-...)
Show SMILES CC1CCSC(N1)=Nc1ccc(CCNc2nc3ccccc3s2)cc1 |w:7.8|
Show InChI InChI=1S/C20H22N4S2/c1-14-11-13-25-20(22-14)23-16-8-6-15(7-9-16)10-12-21-19-24-17-4-2-3-5-18(17)26-19/h2-9,14H,10-13H2,1H3,(H,21,24)(H,22,23)
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Article
PubMed
50n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
Displacement of [125I]pig PPY from human NPY1 receptor expressed in CHOK1 cells by scintillation counting


Bioorg Med Chem Lett 19: 6801-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.048
BindingDB Entry DOI: 10.7270/Q2XP753Z
More data for this
Ligand-Target Pair