BDBM50312201 1-(3-(8-(pyridin-4-ylmethoxy)imidazo[1,2-a]pyrazin-6-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea::CHEMBL1079809

SMILES: FC(F)(F)c1cccc(NC(=O)Nc2cccc(c2)-c2cn3ccnc3c(OCc3ccncc3)n2)c1

InChI Key: InChIKey=VYPKGVPXECFUKL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312201   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50312201 (1-(3-(8-(pyridin-4-ylmethoxy)imidazo[1,2-a]pyrazin...) Show SMILES FC(F)(F)c1cccc(NC(=O)Nc2cccc(c2)-c2cn3ccnc3c(OCc3ccncc3)n2)c1 Show InChI InChI=1S/C26H19F3N6O2/c27-26(28,29)19-4-2-6-21(14-19)33-25(36)32-20-5-1-3-18(13-20)22-15-35-12-11-31-23(35)24(34-22)37-16-17-7-9-30-10-8-17/h1-15H,16H2,(H2,32,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
CGI Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of EphB4 autophosphorylation by cell based assay				Bioorg Med Chem Lett 19: 6991-5 (2009) Article DOI: 10.1016/j.bmcl.2009.10.037 BindingDB Entry DOI: 10.7270/Q2DR2VM3
					More data for this Ligand-Target Pair