BDBM50312386 2-(4-((4,5-bis(4-chlorophenyl)thiazol-2-yl)methoxy)-2-methylphenoxy)acetic acid::CHEMBL1080026

SMILES: Cc1cc(OCc2nc(c(s2)-c2ccc(Cl)cc2)-c2ccc(Cl)cc2)ccc1OCC(O)=O

InChI Key: InChIKey=JSYOXBHBSASSPV-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312386   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50312386 (2-(4-((4,5-bis(4-chlorophenyl)thiazol-2-yl)methoxy...) Show SMILES Cc1cc(OCc2nc(c(s2)-c2ccc(Cl)cc2)-c2ccc(Cl)cc2)ccc1OCC(O)=O Show InChI InChI=1S/C25H19Cl2NO4S/c1-15-12-20(10-11-21(15)32-14-23(29)30)31-13-22-28-24(16-2-6-18(26)7-3-16)25(33-22)17-4-8-19(27)9-5-17/h2-12H,13-14H2,1H3,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	510	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50312386 (2-(4-((4,5-bis(4-chlorophenyl)thiazol-2-yl)methoxy...) Show SMILES Cc1cc(OCc2nc(c(s2)-c2ccc(Cl)cc2)-c2ccc(Cl)cc2)ccc1OCC(O)=O Show InChI InChI=1S/C25H19Cl2NO4S/c1-15-12-20(10-11-21(15)32-14-23(29)30)31-13-22-28-24(16-2-6-18(26)7-3-16)25(33-22)17-4-8-19(27)9-5-17/h2-12H,13-14H2,1H3,(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50312386 (2-(4-((4,5-bis(4-chlorophenyl)thiazol-2-yl)methoxy...) Show SMILES Cc1cc(OCc2nc(c(s2)-c2ccc(Cl)cc2)-c2ccc(Cl)cc2)ccc1OCC(O)=O Show InChI InChI=1S/C25H19Cl2NO4S/c1-15-12-20(10-11-21(15)32-14-23(29)30)31-13-22-28-24(16-2-6-18(26)7-3-16)25(33-22)17-4-8-19(27)9-5-17/h2-12H,13-14H2,1H3,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair