null

SMILES: Cc1cc(OCc2nc(c(o2)-c2ccc(OC(F)(F)F)cc2)-c2ccc(nc2)N2CCOCC2)ccc1OCC(O)=O

InChI Key: InChIKey=YJQWSGKPHYWIRY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50312479   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50312479 (2-(4-((4-(6-Morpholinopyridin-3-yl)-5-(4-(trifluor...) Show SMILES Cc1cc(OCc2nc(c(o2)-c2ccc(OC(F)(F)F)cc2)-c2ccc(nc2)N2CCOCC2)ccc1OCC(O)=O Show InChI InChI=1S/C29H26F3N3O7/c1-18-14-22(7-8-23(18)40-17-26(36)37)39-16-25-34-27(20-4-9-24(33-15-20)35-10-12-38-13-11-35)28(41-25)19-2-5-21(6-3-19)42-29(30,31)32/h2-9,14-15H,10-13,16-17H2,1H3,(H,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Mus musculus)	BDBM50312479 (2-(4-((4-(6-Morpholinopyridin-3-yl)-5-(4-(trifluor...) Show SMILES Cc1cc(OCc2nc(c(o2)-c2ccc(OC(F)(F)F)cc2)-c2ccc(nc2)N2CCOCC2)ccc1OCC(O)=O Show InChI InChI=1S/C29H26F3N3O7/c1-18-14-22(7-8-23(18)40-17-26(36)37)39-16-25-34-27(20-4-9-24(33-15-20)35-10-12-38-13-11-35)28(41-25)19-2-5-21(6-3-19)42-29(30,31)32/h2-9,14-15H,10-13,16-17H2,1H3,(H,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at mouse PPARdelta by FRET assay				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50312479 (2-(4-((4-(6-Morpholinopyridin-3-yl)-5-(4-(trifluor...) Show SMILES Cc1cc(OCc2nc(c(o2)-c2ccc(OC(F)(F)F)cc2)-c2ccc(nc2)N2CCOCC2)ccc1OCC(O)=O Show InChI InChI=1S/C29H26F3N3O7/c1-18-14-22(7-8-23(18)40-17-26(36)37)39-16-25-34-27(20-4-9-24(33-15-20)35-10-12-38-13-11-35)28(41-25)19-2-5-21(6-3-19)42-29(30,31)32/h2-9,14-15H,10-13,16-17H2,1H3,(H,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.49E+3	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50312479 (2-(4-((4-(6-Morpholinopyridin-3-yl)-5-(4-(trifluor...) Show SMILES Cc1cc(OCc2nc(c(o2)-c2ccc(OC(F)(F)F)cc2)-c2ccc(nc2)N2CCOCC2)ccc1OCC(O)=O Show InChI InChI=1S/C29H26F3N3O7/c1-18-14-22(7-8-23(18)40-17-26(36)37)39-16-25-34-27(20-4-9-24(33-15-20)35-10-12-38-13-11-35)28(41-25)19-2-5-21(6-3-19)42-29(30,31)32/h2-9,14-15H,10-13,16-17H2,1H3,(H,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair