BDBM50312545 (1R,2R,4S)-2-(6-chloro-5-phenylpyridin-3-yl)-7-azabicyclo[2.2.1]heptane::CHEMBL1075632
SMILES: Clc1ncc(cc1-c1ccccc1)[C@H]1C[C@@H]2CC[C@H]1N2
InChI Key: InChIKey=CCCKJPGFLXNAOM-SQWLQELKSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat)) | BDBM50312545 ((1R,2R,4S)-2-(6-chloro-5-phenylpyridin-3-yl)-7-aza...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex after 4 hrs by scintillation counting | J Nat Prod 73: 306-12 (2010) Article DOI: 10.1021/np9006124 BindingDB Entry DOI: 10.7270/Q2TQ61PZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor (Rattus norvegicus (Rat)) | BDBM50312545 ((1R,2R,4S)-2-(6-chloro-5-phenylpyridin-3-yl)-7-aza...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Displacement of [3H]iodo-MLA from alpha7 nAChR in rat cerebral cortex after 2 hrs by scintillation counting | J Nat Prod 73: 306-12 (2010) Article DOI: 10.1021/np9006124 BindingDB Entry DOI: 10.7270/Q2TQ61PZ | |||||||||||
More data for this Ligand-Target Pair |