BDBM50312758 (S)-N1-(5-(3-ethyl-1H-indazol-5-yl)-1,3,4-thiadiazol-2-yl)-3-phenylpropane-1,2-diamine::CHEMBL1081426

SMILES: CCc1n[nH]c2ccc(cc12)-c1nnc(NC[C@@H](N)Cc2ccccc2)s1

InChI Key: InChIKey=ANYCWFADTHVOPB-HNNXBMFYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312758   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50312758 ((S)-N1-(5-(3-ethyl-1H-indazol-5-yl)-1,3,4-thiadiaz...) Show SMILES CCc1n[nH]c2ccc(cc12)-c1nnc(NC[C@@H](N)Cc2ccccc2)s1 |r| Show InChI InChI=1S/C20H22N6S/c1-2-17-16-11-14(8-9-18(16)24-23-17)19-25-26-20(27-19)22-12-15(21)10-13-6-4-3-5-7-13/h3-9,11,15H,2,10,12,21H2,1H3,(H,22,26)(H,23,24)/t15-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of AKT1 after 10 mins by [gamma33]ATP assay				Bioorg Med Chem Lett 20: 1652-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.046 BindingDB Entry DOI: 10.7270/Q21836MC
					More data for this Ligand-Target Pair