BDBM50313121 3-(3-chlorophenylsulfonyl)-1-(1-methylpyrrolidin-3-yl)-1H-indole::CHEMBL1086719

SMILES: CN1CCC(C1)n1cc(c2ccccc12)S(=O)(=O)c1cccc(Cl)c1

InChI Key: InChIKey=INCWGVPGPVQEOT-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313121   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313121 (3-(3-chlorophenylsulfonyl)-1-(1-methylpyrrolidin-3...) Show SMILES CN1CCC(C1)n1cc(c2ccccc12)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H19ClN2O2S/c1-21-10-9-15(12-21)22-13-19(17-7-2-3-8-18(17)22)25(23,24)16-6-4-5-14(20)11-16/h2-8,11,13,15H,9-10,12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313121 (3-(3-chlorophenylsulfonyl)-1-(1-methylpyrrolidin-3...) Show SMILES CN1CCC(C1)n1cc(c2ccccc12)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H19ClN2O2S/c1-21-10-9-15(12-21)22-13-19(17-7-2-3-8-18(17)22)25(23,24)16-6-4-5-14(20)11-16/h2-8,11,13,15H,9-10,12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced intracellular cAMP level after 10 min...				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair