BDBM50313132 3-(3-fluorophenylsulfonyl)-1-(piperidin-3-yl)-1H-indole::CHEMBL1081095

SMILES: Fc1cccc(c1)S(=O)(=O)c1cn(C2CCCNC2)c2ccccc12

InChI Key: InChIKey=ZDQCZXVTNASVOV-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313132 (3-(3-fluorophenylsulfonyl)-1-(piperidin-3-yl)-1H-i...) Show SMILES Fc1cccc(c1)S(=O)(=O)c1cn(C2CCCNC2)c2ccccc12 Show InChI InChI=1S/C19H19FN2O2S/c20-14-5-3-7-16(11-14)25(23,24)19-13-22(15-6-4-10-21-12-15)18-9-2-1-8-17(18)19/h1-3,5,7-9,11,13,15,21H,4,6,10,12H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313132 (3-(3-fluorophenylsulfonyl)-1-(piperidin-3-yl)-1H-i...) Show SMILES Fc1cccc(c1)S(=O)(=O)c1cn(C2CCCNC2)c2ccccc12 Show InChI InChI=1S/C19H19FN2O2S/c20-14-5-3-7-16(11-14)25(23,24)19-13-22(15-6-4-10-21-12-15)18-9-2-1-8-17(18)19/h1-3,5,7-9,11,13,15,21H,4,6,10,12H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	56	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as effect on 5HT-induced intracellular cAMP level after 10 mins by ra...				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair