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SMILES: COc1ccc2n(cc(c2c1)S(=O)(=O)c1cccc(F)c1)C1CCCN(C)C1

InChI Key: InChIKey=UARNXWMBTDEUME-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313134   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM50313134
PNG
(3-(3-fluorophenylsulfonyl)-5-methoxy-1-(1-methylpi...)
Show SMILES COc1ccc2n(cc(c2c1)S(=O)(=O)c1cccc(F)c1)C1CCCN(C)C1
Show InChI InChI=1S/C21H23FN2O3S/c1-23-10-4-6-16(13-23)24-14-21(19-12-17(27-2)8-9-20(19)24)28(25,26)18-7-3-5-15(22)11-18/h3,5,7-9,11-12,14,16H,4,6,10,13H2,1-2H3
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Similars
Article
PubMed
 68n/an/an/an/an/an/an/an/a



Wyeth Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs

Bioorg Med Chem Lett 20: 1657-60 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.073
BindingDB Entry DOI: 10.7270/Q2ZC830C
More data for this
Ligand-Target Pair