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SMILES: Fc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2cccc(F)c12

InChI Key: InChIKey=JKIQJNZUUPEZKI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313142   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM50313142
PNG
(4-fluoro-3-(3-fluorophenylsulfonyl)-1-(pyrrolidin-...)
Show SMILES Fc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2cccc(F)c12
Show InChI InChI=1S/C18H16F2N2O2S/c19-12-3-1-4-14(9-12)25(23,24)17-11-22(13-7-8-21-10-13)16-6-2-5-15(20)18(16)17/h1-6,9,11,13,21H,7-8,10H2
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Article
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 18n/an/an/an/an/an/an/an/a



Wyeth Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs

Bioorg Med Chem Lett 20: 1657-60 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.073
BindingDB Entry DOI: 10.7270/Q2ZC830C
More data for this
Ligand-Target Pair