null

SMILES: Fc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ccc(F)cc12

InChI Key: InChIKey=YXCBVZRAABWHKG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313143   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313143 (5-fluoro-3-(3-fluorophenylsulfonyl)-1-(pyrrolidin-...) Show SMILES Fc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ccc(F)cc12 Show InChI InChI=1S/C18H16F2N2O2S/c19-12-2-1-3-15(8-12)25(23,24)18-11-22(14-6-7-21-10-14)17-5-4-13(20)9-16(17)18/h1-5,8-9,11,14,21H,6-7,10H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313143 (5-fluoro-3-(3-fluorophenylsulfonyl)-1-(pyrrolidin-...) Show SMILES Fc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ccc(F)cc12 Show InChI InChI=1S/C18H16F2N2O2S/c19-12-2-1-3-15(8-12)25(23,24)18-11-22(14-6-7-21-10-14)17-5-4-13(20)9-16(17)18/h1-5,8-9,11,14,21H,6-7,10H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as effect on 5HT-induced intracellular cAMP level after 10 mins by ra...				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair