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SMILES: Fc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ccc(Cl)cc12

InChI Key: InChIKey=HOHFJDODOVXAPZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313145   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM50313145
PNG
(5-chloro-3-(3-fluorophenylsulfonyl)-1-(pyrrolidin-...)
Show SMILES Fc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ccc(Cl)cc12
Show InChI InChI=1S/C18H16ClFN2O2S/c19-12-4-5-17-16(8-12)18(11-22(17)14-6-7-21-10-14)25(23,24)15-3-1-2-13(20)9-15/h1-5,8-9,11,14,21H,6-7,10H2
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Article
PubMed
 15n/an/an/an/an/an/an/an/a



Wyeth Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs

Bioorg Med Chem Lett 20: 1657-60 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.073
BindingDB Entry DOI: 10.7270/Q2ZC830C
More data for this
Ligand-Target Pair