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SMILES: C[C@H](Nc1nc(Nc2ncc(C)s2)cc(n1)N1CCN(C)CC1)c1ccc(F)cn1

InChI Key: InChIKey=RIZYPSQRIHNRNS-AWEZNQCLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313160   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))		BDBM50313160
PNG
((S)-N2-(1-(5-fluoropyridin-2-yl)ethyl)-6-(4-methyl...)
Show SMILES C[C@H](Nc1nc(Nc2ncc(C)s2)cc(n1)N1CCN(C)CC1)c1ccc(F)cn1 |r|
Show InChI InChI=1S/C20H25FN8S/c1-13-11-23-20(30-13)26-17-10-18(29-8-6-28(3)7-9-29)27-19(25-17)24-14(2)16-5-4-15(21)12-22-16/h4-5,10-12,14H,6-9H2,1-3H3,(H2,23,24,25,26,27)/t14-/m0/s1
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MMDB

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Article
PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



AstraZeneca R&D Boston

Curated by ChEMBL


Assay Description
Inhibition of human ERG

Bioorg Med Chem Lett 20: 1669-73 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.091
BindingDB Entry DOI: 10.7270/Q2PV6KG1
More data for this
Ligand-Target Pair