BDBM50313298 (1R,5S)-8-(4-tert-butylphenylsulfonyl)-8-azabicyclo[3.2.1]octane-3,3-diol::CHEMBL1079975

SMILES: CC(C)(C)c1ccc(cc1)S(=O)(=O)N1[C@H]2CC[C@@H]1CC(O)(O)C2

InChI Key: InChIKey=XIYKXNLPFUZIOT-OKILXGFUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313298   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50313298 ((1R,5S)-8-(4-tert-butylphenylsulfonyl)-8-azabicycl...) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1[C@H]2CC[C@@H]1CC(O)(O)C2 |r| Show InChI InChI=1S/C17H25NO4S/c1-16(2,3)12-4-8-15(9-5-12)23(21,22)18-13-6-7-14(18)11-17(19,20)10-13/h4-5,8-9,13-14,19-20H,6-7,10-11H2,1-3H3/t13-,14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cortisone from mouse 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assay				Bioorg Med Chem Lett 20: 1551-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.082 BindingDB Entry DOI: 10.7270/Q2NV9JC3
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50313298 ((1R,5S)-8-(4-tert-butylphenylsulfonyl)-8-azabicycl...) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1[C@H]2CC[C@@H]1CC(O)(O)C2 |r| Show InChI InChI=1S/C17H25NO4S/c1-16(2,3)12-4-8-15(9-5-12)23(21,22)18-13-6-7-14(18)11-17(19,20)10-13/h4-5,8-9,13-14,19-20H,6-7,10-11H2,1-3H3/t13-,14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cortisone from human 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assay				Bioorg Med Chem Lett 20: 1551-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.082 BindingDB Entry DOI: 10.7270/Q2NV9JC3
					More data for this Ligand-Target Pair